Skyscape was selected to provide the software infrastructure and application that served as a base for a National Institutes of Health (NIH) study with The Mount Sinai Medical Center in New York.

Together Mount Sinai and Skyscape developed this handheld solution for the treatment of cardiology patients as part of a $1 million grant from the National Heart, Lung and Blood Institute, part of the National Institutes of Health. The goal of the two-year research project, titled Palm Risk-Outcomes Manager & Patient Tracker (PROMPT), was to determine how the use of PDAs by their physicians benefits cardiology patients. This customized solution for the hospital enabled the integration between PDAs and other enterprise systems used by medical practitioners.

The PROMPT Program at The Mount Sinai Hospital, which ran from September 2000 to September 2002, included approximately 14,500 patients as well as 125 cardiologists, divided into three study groups, including one control group. The program requirements included meeting the specific needs of studying cardiovascular risk factors, such as cholesterol levels and blood pressure, and monitoring physician behavior. The solution used by the cardiologists allowed patient data to be collected on Palm 5x PDAs at the time of a clinical encounter relating to cardiovascular risk, displayed previously captured data, prompted physicians to counsel lifestyle changes, and calculated risk scores and target clinical parameters.

The Skyscape solution enabled physicians to collect data and transmit it to a central server using an automated, bi-directional synchronization process that uploaded the user-collected data from a physician's PDA and appended records in the network database, and downloaded demographics and appointments from the network database to the PDA. Additionally, the Skyscape solution enabled the network database to receive data from hospital enterprise systems and create queries built to answer research questions, support project surveillance and administration, quarterly reports or chart extraction. This is the first time cardiologists have had access to dynamic content systems for their handheld computers, which is based on an evolution of Skyscape's smARTlink technology.